Human Behavior Essay

At the beginning of the strike, Lorenzo (played by Noah Banks and also Zack OM anyey Greenburg) is a bright and vibrant refreshing-fangled countersign living in the Comoros Islands, as his father Augusto (played by Nick Nolte) kit and boodle for the World Bank and is stationed there. However, when his p atomic number 18nts relocate to the unite States, he begins to show neurological problems, much(prenominal) as release of hearing, tantrums, etc. The boy is diagnosed as having adrenoleukodystrophy (ALD), which is fatal within dickens years. Failing to find a rectify capable of treating their sons lofty ailment, Augusto and his wife Michaela (Susan Sarandon) set out on a mission to find a treatment to save their child. In their quest, the Odones brushwood with doctors, scientists, and subscribe to groups, who are skeptical that anything could be done about ALD, much little by laypeople. But they persist, setting up camp in medical libraries, reviewing wildcat experimen ts, enlisting the aid of Professor Gus Nikolais (played by Peter Ustinov), badgering researchers, questioning aggrandizement doctors all over the humanness, and even organizing an foreign symposium about the unhealthiness.Despite research dead-ends, the crime of watching their sons wellness decline, and being surrounded by skeptics (including the coordinators of the support group they at exd), they persist until they finally pass on upon a therapy involving adding a current signifier of inunct (actually containing two specific keen-sighted mountain chain rich acids, isolated from rapeseed layaboutola oil and olive oil) to their sons diet. They hitting over 100 firms approximately the world until they find an elderly British chemist (Don Suddaby, who plays himself in a cameo role) working for Croda global who is willing to take on the argufy of di withaling the proper turnula. The oil, erucic acid, proves successful in publicizing the accruement of the very long chain dipper acids in the brain that had been causing their sons steady decline, thereby game the progression of the disease.There is still a great deal of neurological modify remaining which could not be converse unless new treatments could be found to renew the bulb sheath (a lipid insulator) around the impertinences. The father is seen taking on the new challenge of organizing biomedical efforts to heal myelin deterioration in patients (see The Myelin Project). The film ends with Lorenzo at the age of 14 showing definite improvement (he could swallow for himself and outcome yes or no questions by blinking) scarcely indicating more medical research is still needed. The end c ceriseits of the film pecker that Lorenzo has also regained his sight and is learning to hold a computer.AdrenoleukodystrophyDefinitionAdrenoleukodystrophy is a idealistic genetic disease characterized by a hurt of myelin surrounding nerve cells in the brain and progressive suprarenal gland gla nd gland dys ply.DescriptionAdrenoleukodystrophy (ALD) is a fragment of a group of diseases, leukodystrophies, that cause damage to the myelin sheath of nerve cells. more or less one in 100,000 people is bear upon by ALD. There are ternary basic forms of ALD childhood, adult-onset, and neonatal. The childhood form of the disease is the classical form and is the near severe. childhood ALD is progressive and usually leads to total check or death. It affects only boys because the genetic shift is sex-linked (carried on the X chromosome). blast usually occurs between ages four and ten and send word include many diametrical types, not all of which appear together. The most car park prognostics are behavioral problems and suffering memory. Other symptoms frequently seen are loss of vision, seizures, poorly articulated speech, difficulty swallowing, deafness, problems with yard and coordination, fatigue, increased skin pigmentation, and progressive dementia.The adult-onset form of the disease, also called adrenomyeloneuropathy, is milder, progresses slowly, is usually associated with a radiation diagram life span, and usually appears between ages 21-35. Symptoms may include progressive stiffness, weakness, or paralysis of the lower limbs and loss of coordination. Brain function deterioration may also been seen. Women who are carriers of the disease occasionally experience the corresponding symptoms, as well as others, including ataxia, hypertonia ( profuse brawniness tone), mild peripheral neuropathy, and urinary problems. The neonatal form affects both virile and female infants and may produce moral retardation, facial abnormalities, seizures, retinal degeneration, poor energy tone, enlarged liver, and adrenal disfunction. Neonatal ALD usually progresses rapidly.Causes and symptomsThe genetic defect in ALD causes a decrease in the ability to depress very long chain fatty acids. These build up in the adrenal glands, brain, plasma, and fibro blasts. The build-up of very long chain fatty acids interferes with the ability of the adrenal gland to substitute cholesterol into steroids and causes demyelination of nerves in the exsanguine matter of the brain. Demyelinated nerve cells are uneffective to function properly.DiagnosisDiagnosis is do based on observed symptoms, a biochemical outpouring, and a family account. The biochemical test detects elevated levels of very long chain fatty acids in samples from amniocentesis, chorionic villi, plasma, red fund cells, or fibroblasts. A family history may indicate the likelihood of ALD because the disease is carried on the X-chromosome by the female tune of families.Biosynthesis (also called biogenesis or anabolism) is an enzyme-catalyzed process in cells of living organisms by which substrates are converted to more decomposable harvest-times.1 The biosynthesis process often consists of some(prenominal) enzymatic steps in which the product of one step is apply as substr ate in the following step. Examples for much(prenominal) multi-step biosynthetic pathways are those for the production of blood clots,amino acids, fatty acids, and natural products.2 Biosynthesis plays a major role in all cells, and many dedicated metabolic routes have constitute general metabolism. Six organelles in the cell are involved in biosynthesis ribosomes, chloroplasts, smooth endoplasmic reticulum, rough endoplasmic reticulum, plastids, and Golgi bodies.3 mania (taken from Latin, originally meaning madness, from de- without + ment, the commencement of mens mind) is a serious loss of global cognitive ability in a previously unimpaired person, beyond what might be expected from normal aging. It may be static, the result of a unique global brain injury, or progressive, resulting in long-term decline cod to damage or disease in the body. Although dementia is far more common in the geriatric population (about 5% of those over 65 are say to be involved),1 it can occur to begin with the age of 65, in which case it is termed earlier onset dementia.2 Dementia is not a single disease, but a non-specific syndrome (i.e., set of signs and symptoms). Affected cognitive areas can be memory, attention, language, and problem solving. Normally, symptoms must be present for at least 6 months to support a diagnosis.3 Cognitive dysfunction of shorter duration is called delirium.Dysphagia is the medical term for the symptom of difficulty in swallowing.123 Although classified low symptoms and signs in ICD-10,4 the term is sometimes used as a condition in its own right.567 Sufferers are sometimes unwitting of their dysphagia. Spasticity is a feature of altered impecunious muscle performance in muscle tone involving hypertonia it is also referred to as an unusual tightness, stiffness, or bust of muscles. The sound out spasm comes from the Greek word (spasmos), meaning drawing, pulling.Clinically spasticity is defined as velocity dependent resistance to stretch , where a lack of inhibition results in excessive contraction of the muscles, ultimately leading to hyperflexia (overly flexed joints). It broadly occurs in disorders of the central nervous agreement (CNS) affecting the upper motor neuron in the form of a lesion, such as spastic diplegia, but it can also present in motley types of multiple sclerosis, where it occurs as a symptom of the progressively-worsening attacks on myelin sheaths and is thus uncorrelated to the types of spasticity present in neuromuscular noetic palsy rooted spasticity disorders. DefinitionA seizure happens when there are certain types of abnormal electrical activity in the brain. During a seizure, you may*Lose spirit* Stare into space* Have convulsions (abnormal choppy of the muscles)* Experience abnormalities of sensation or perception